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021-54845833/15800441009
中文名称： 兔抗GCLC多克隆抗体
抗 原： GCLC
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Background: |
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
GCLC |
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Immunogen: |
Fusion protein of human GCLC |
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Full name: |
glutamate-cysteine ligase, catalytic subunit |
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Synonyms： |
GCL; GCS; GLCL; GLCLC |
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SwissProt: |
P48506 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human brain |
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IHC Recommend dilution: |
25-100 |
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WB Predicted band size: |
73 kDa |
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WB Positive control: |
Raw264.7，A549，Hepg2 and Jurkat cell |
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WB Recommended dilution: |
500-2000 |
