兔抗ADH5多克隆抗体

Background:

This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.

Applications:

ELISA, WB

Name of antibody:

ADH5

Immunogen:

Fusion protein of human ADH5

Full name:

alcohol dehydrogenase 5 (class III), chi polypeptide

Synonyms:

FDH; ADHX; ADH-3; FALDH; GSNOR; GSH-FDH; HEL-S-60p

SwissProt:

P11766

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

40 kDa

WB Positive control:

Mouse kidney tissue and Human fetal brain tissue lysates

WB Recommended dilution:

500-2000