小鼠抗PPAT单克隆抗体

Background:

The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. It is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosythetic pathway. This gene and PAICS/AIRC gene, a bifunctional enzyme catalyzing steps six and seven of this pathway, are located in close proximity on chromosome 4, and divergently transcribed from an intergenic region. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.

Applications:

WB, IHC

Name of antibody:

PPAT

Immunogen:

Fusion protein of human PPAT

Full name:

phosphoribosyl pyrophosphate amidotransferase (PPAT)

Synonyms:

ATASE; GPAT; PRAT

SwissProt:

Q06203

IHC positive control:

human liver tissue and carcinoma of human liver tissue; human pancreas tissue and carcinoma of human thyroid tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

57 kDa

WB Positive control:

Human testis tissue, Human omentum tissue, Human uterus tissue, Human brain tissue, Human ovary tissue lysates

WB Recommended dilution:

200-1000