Background: |
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death. |
Applications: |
WB, IHC |
Name of antibody: |
PPIF |
Immunogen: |
Fusion protein of human PPIF |
Full name: |
peptidylprolyl isomerase F |
Synonyms: |
CYP3; CypD; CyP-M; Cyp-D |
SwissProt: |
P30405 |
IHC positive control: |
Human liver cancer |
IHC Recommend dilution: |
500-1000 |
WB Predicted band size: |
22 KD |
WB Positive control: |
A431, Hela, HepG2 and K562 cell lysates |
WB Recommended dilution: |
500-2000 |