兔抗GAS6多克隆抗体

Background:

This gene product is a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation, and may play a role in thrombosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.

Applications:

ELISA, IHC

Name of antibody:

GAS6

Immunogen:

Synthetic peptide of human GAS6

Full name:

growth arrest-specific 6

Synonyms：

AXSF, AXLLG

SwissProt:

Q14393

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human ovarian cancer and Human cervical cancer

IHC Recommend dilution:

10-50