Background: |
This gene encodes a member of the parvin family of actin-binding proteins, which play a role in cytoskeleton organization and cell adhesion. These proteins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. This family member binds to alphaPIX and alpha-actinin, and it can inhibit the activity of integrin-linked kinase. This protein also functions in tumor suppression. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]. |
Applications: |
WB, IHC, IF |
Name of antibody: |
PARVB |
Immunogen: |
Fusion protein of human PARVB |
Full name: |
parvin, beta (PARVB), transcript variant 2 |
Synonyms: |
CGI-56 |
SwissProt: |
Q9HBI1 |
IHC positive control: |
human liver tissue |
IHC Recommend dilution: |
30-150 |
WB Predicted band size: |
42 kDa |
WB Positive control: |
SVT2, A549, PC12 cell lysates |
WB Recommended dilution: |
500-2000 |