Background: |
Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis. |
Applications: |
WB, IHC |
Name of antibody: |
TALDO1 |
Immunogen: |
Fusion protein of human TALDO1 |
Full name: |
transaldolase 1 |
Synonyms: |
TAL; TALH; TAL-H; TALDOR |
SwissProt: |
P37837 |
IHC positive control: |
Human breast cancer and Human kidney tissue; Human liver cancer and Human pancreas tissue |
IHC Recommend dilution: |
200-500 |
WB Predicted band size: |
38 KD |
WB Positive control: |
A431, Hela, HepG2 cell lysates |
WB Recommended dilution: |
500-2000 |