小鼠抗STC1单克隆抗体

Background:

This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers.

Applications:

WB

Name of antibody:

STC1

Immunogen:

Fusion protein of human STC1

Full name:

stanniocalcin 1

Synonyms:

STC

SwissProt:

P52823

WB Predicted band size:

28 KD

WB Positive control:

MDCK cell lysate

WB Recommended dilution:

500-2000