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Background: |
This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene. |
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Applications: |
WB |
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Name of antibody: |
ADCY5 |
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Immunogen: |
Synthesized peptide derived from internal of human ADCY5. |
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Full name: |
adenylate cyclase 5 |
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Synonyms： |
AC5; FDFM |
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SwissProt: |
O95622 |
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WB Predicted band size: |
139 kDa |
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WB Positive control: |
COLO205 cells lysate |
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WB Recommended dilution: |
500-3000 |
