宿 主: Mouse
Background: |
The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements. [provided by RefSeq, Jul 2008]. |
Applications: |
WB, IF |
Name of antibody: |
SHPK |
Immunogen: |
Fusion protein of human SHPK |
Full name: |
sedoheptulokinase (SHPK) |
Synonyms: |
CARKL; SHK |
SwissProt: |
Q9UHJ6 |
WB Predicted band size: |
51 kDa |
WB Positive control: |
HepG2, SVT2 cell lysates |
WB Recommended dilution: |
200-1000 |