小鼠抗SERPINE1单克隆抗体

Background:

This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, WB

Name of antibody:

SERPINE1

Immunogen:

Fusion protein of human SERPINE1

Full name:

serpin family E member 1

Synonyms:

PAI; PAI1; PAI-1; PLANH1

SwissProt:

P05121

WB Predicted band size:

45 kDa

WB Positive control:

BGC823 whole cell lysate

WB Recommended dilution:

200-1000