Background: |
The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]. |
Applications: |
WB, IHC |
Name of antibody: |
SDCBP |
Immunogen: |
Fusion protein of human SDCBP |
Full name: |
syndecan binding protein (syntenin) (SDCBP), transcript variant 1 |
Synonyms: |
MDA-9; MDA9; ST1; SYCL; TACIP18 |
SwissProt: |
O00560 |
IHC positive control: |
adenocarcinoma of human ovary tissue and adenocarcinoma of human endometrium tissue; human liver tissue |
IHC Recommend dilution: |
30-150 |
WB Predicted band size: |
32 kDa |
WB Positive control: |
HepG2, Hela, A549, Jurkat, MCF-7 cell lysates |
WB Recommended dilution: |
500-2000 |