小鼠抗SAA1单克隆抗体

Background:

This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11.

Applications:

ELISA, WB

Name of antibody:

SAA1

Immunogen:

Fusion protein of human SAA1

Full name:

serum amyloid A1

Synonyms:

SAA; PIG4; SAA2; TP53I4

SwissProt:

P02735

WB Predicted band size:

14 kDa

WB Positive control:

MCF-7 whole cell lysate

WB Recommended dilution:

500-2000