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    小鼠抗RYBP单克隆抗体

    小鼠抗RYBP单克隆抗体

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    • 品牌 : 通蔚生物
    • 目录号 : TW11941
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
    • 商品库存：20
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中文名称: 小鼠抗RYBP单克隆抗体

英文名称: Anti-RYBP mouse monoclonal antibody

别    名: AAP1; DEDAF; YEAF1; APAP-1

储    存: 冷冻（-20℃） 避光

抗    原: RYBP

宿    主: Mouse

反应种属: Human , Dog , Monkey , Mouse

相关类别: 一抗

标 记 物: Unconjugate

克隆类型: mouse monoclonal

技术规格

Background:

The products of the Polycomb group (PcG) of genes are necessary for the maintenance of transcriptional repression of a number of important developmental genes, including the homeotic genes. RYBP is a member of the mammalian polycomb complex. RYBP (RING1- and YY1-binding protein) interacts specifically with the E2F2 and E2F3 family members, dependent on the marked box domain in these proteins. YY1 and RYBP, in combination with either E2F2 or E2F3, can stimulate Cdc6 promoter activity synergistically, at G1/S of the cell cycle. RYBP also complexes with both RING1 proteins (RING1 and RING1B) and with M33, two mutually interacting sets of proteins of the mammalian Polycomb complex. RING1 binds RYBP and M33 through the same C-terminal domain, whereas the RYBP-M33 interaction takes place through an M33 domain not involved in binding. RYBP is widely expressed with highest levels in lymphoid tissues and placenta.

Applications:

WB

Name of antibody:

RYBP

Immunogen:

Fusion protein of human RYBP

Full name:

RING1 and YY1 binding protein (RYBP)

Synonyms:

AAP1; DEDAF; YEAF1; APAP-1

SwissProt:

Q8N488

WB Predicted band size:

25 kDa

WB Positive control:

Hela, SVT2, A549, COS7, Jurkat, MDCK cell lysates

WB Recommended dilution:

500-2000