Background: |
The protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis. A pseudogene of this gene is found on chromosome 1. |
Applications: |
WB |
Name of antibody: |
RNF4 |
Immunogen: |
Fusion protein of human RNF4 |
Full name: |
ring finger protein 4 |
Synonyms: |
SLX5; SNURF; RES4-26 |
SwissProt: |
P78317 |
WB Predicted band size: |
21 KD |
WB Positive control: |
Hela, MCF7, PC-12 cell lysates |
WB Recommended dilution: |
500-2000 |