克隆类型: mouse monoclonal
技术规格
Background: |
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. RIOK2 (RIO kinase 2) is a 552 amino acid protein that contains one protein kinase domain and belongs to the RIO subfamily of atypical Ser/Thr protein kinases. RIOK2 functions to catalyze the ATP-dependent phosphorylation of target proteins and is thought to play an important role in ribosome biogenesis and cell cycle progression. |
Applications: |
WB, IHC, IF |
Name of antibody: |
RIOK2 |
Immunogen: |
Fusion protein of human RIOK2 |
Full name: |
RIO kinase 2 (RIOK2), transcript variant 1 |
Synonyms: |
RIO2 |
SwissProt: |
Q9BVS4 |
IHC positive control: |
adenocarcinoma of human ovary tissue |
IHC Recommend dilution: |
30-150 |
WB Predicted band size: |
63 kDa |
WB Positive control: |
HepG2, Hela, SVT2, A549, COS7, Jurkat, MCF-7 cell lysates |
WB Recommended dilution: |
500-2000 |