别 名: recombination signal binding protein for immunoglobulin kappa J region; SUH; csl; AOS3; CBF1; KBF2; RBP-J; RBPJK; IGKJRB; RBPSUH; IG
Background: |
The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9. |
Applications: |
WB |
Name of antibody: |
RBPJ |
Immunogen: |
Fusion protein of human RBPJ |
Full name: |
recombination signal binding protein for immunoglobulin kappa J region |
Synonyms: |
SUH; csl; AOS3; CBF1; KBF2; RBP-J; RBPJK; IGKJRB; RBPSUH; IGKJRB1 |
SwissProt: |
Q06330 |
WB Predicted band size: |
56 KD |
WB Positive control: |
293T, K562, HepG2, Hela, MCF7 cell lysates |
WB Recommended dilution: |
200-1000 |