Background: |
This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12. |
Applications: |
WB |
Name of antibody: |
RACGAP1 |
Immunogen: |
Fusion protein of human RACGAP1 |
Full name: |
Rac GTPase activating protein 1 |
Synonyms: |
CYK4; ID-GAP; HsCYK-4; MgcRacGAP |
SwissProt: |
Q9H0H5 |
WB Predicted band size: |
71 KD |
WB Positive control: |
K562, COS7, Hela cell lysates |
WB Recommended dilution: |
500-2000 |