小鼠抗RAB21单克隆抗体

Background:

This gene belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion and migration. Expression of this gene is associated with a poor prognosis for glioma patients. This gene is downregulated by the tumor suppressor miR-200b, and miRNA-200b is itself downregulated in glioma tissues.

Applications:

WB, IHC, IF

Name of antibody:

RAB21

Immunogen:

Fusion protein of human RAB21

Full name:

RAB21, member RAS oncogene family (RAB21)

Synonyms:

KIAA0118

SwissProt:

Q9UL25

IHC positive control:

human prostate tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

24 kDa

WB Positive control:

HepG2, Hela, SVT2, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates

WB Recommended dilution:

500-2000