兔抗ACTA1多克隆抗体

Background:

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.

Applications:

ELISA, WB

Name of antibody:

ACTA1

Immunogen:

Fusion protein of human ACTA1

Full name:

actin, alpha 1, skeletal muscle

Synonyms：

ACTA; ASMA; CFTD; MPFD; NEM1; NEM2; NEM3; CFTD1; CFTDM

SwissProt:

P68133

ELISA Recommended dilution:

1000-2000

WB Predicted band size:

42 kDa

WB Positive control:

Mouse heart and muscle tissue

WB Recommended dilution:

200-1000