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021-54845833/15800441009
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Fusion protein corresponding to a region derived from 23-225 amino acids of human ICAM4 |
技术规格
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Full name: |
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) |
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Synonyms: |
LW; CD242 |
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Swissprot: |
Q14773 |
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Gene Accession: |
BC000046 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
