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021-54845833/15800441009
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Fusion protein corresponding to C terminal 300 amino acids of human HSPH1 |
技术规格
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Full name: |
Heat shock 105kDa/110kDa protein 1 |
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Synonyms: |
HSP105; HSP105A; HSP105B; NY-CO-25 |
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Swissprot: |
Q92598 |
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Gene Accession: |
BC037553 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Heat shock protein 105 kDa is a protein that in humans is encoded by the HSPH1 gene. Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities. Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells. Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity. |
