Fusion protein corresponding to C terminal 300 amino acids of human HSPD1 |
技术规格
Full name: |
heat shock 60kDa protein 1 (chaperonin) |
Synonyms: |
HLD4, CPN60, GROEL, HSP60, HSP65, SPG13, HSP-60, HuCHA60 |
Swissprot: |
P10809 |
Gene Accession: |
BC067082 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. |