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Fusion protein corresponding to a region derived from 531-641 amino acids of human HSPA1A |
技术规格
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Full name: |
heat shock 70kDa protein 1A |
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Synonyms: |
HSP72, HSPA1, HSP70I, HSP70-1, HSP70-1A |
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Swissprot: |
P0DMV8 |
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Gene Accession: |
BC002453 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. |
