购物车
帮助
021-54845833/15800441009
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Background: |
Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed:3198760, PubMed:2033050, PubMed:28240246). By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed:23202369). May play a role in neutrophil transendothelial migration, probably when associated with CD177 (PubMed:22266279). |
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Applications: |
WB |
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Name of antibody: |
PRTN3 |
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Immunogen: |
Fusion protein of human PRTN3 |
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Full name: |
proteinase 3 |
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Synonyms: |
MBN; MBT; NP4; P29; PR3; ACPA; AGP7; NP-4; PR-3; CANCA; C-ANCA |
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SwissProt: |
P24158 |
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WB Predicted band size: |
28 KD |
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WB Positive control: |
Human spleen tissue lysate |
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WB Recommended dilution: |
200-1000 |
