Fusion protein corresponding to a region derived from 1-146 amino acids of human HDAC6 |
技术规格
Full name: |
histone deacetylase 6 |
Synonyms: |
HD6; JM21; CPBHM |
Swissprot: |
Q9UBN7 |
Gene Accession: |
BC005872 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. |