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021-54845833/15800441009
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技术规格
Background:
LRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-kappaB and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530.
Applications:
ELISA, WB, IHC
Name of antibody:
LRRC19
Immunogen:
Fusion protein of human LRRC19
Full name:
leucine rich repeat containing 19
SwissProt:
Q9H756
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human thyroid cancer and Human colorectal cancer
IHC Recommend dilution:
25-100
WB Predicted band size:
42 kDa
WB Positive control:
A172 cell and mouse kidney tissue
WB Recommended dilution:
500-2000
