Background: |
This gene encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome. |
Applications: |
ELISA, IHC |
Name of antibody: |
LRPPRC |
Immunogen: |
Synthetic peptide of human LRPPRC |
Full name: |
leucine-rich pentatricopeptide repeat containing |
Synonyms: |
LSFC, GP130, LRP130, CLONE-23970 |
SwissProt: |
P42704 |
ELISA Recommended dilution: |
1000-2000 |
IHC positive control: |
Human colon cancer and Human ovarian cancer |
IHC Recommend dilution: |
15-50 |