Background: |
This gene encodes a member of a subfamily of LIM domain proteins that are characterized by an N-terminal proline-rich region and three C-terminal LIM domains. The encoded protein localizes to the cell periphery in focal adhesions and may be involved in cell-cell adhesion and cell motility. This protein also shuttles through the nucleus and may function as a transcriptional co-activator. This gene is located at the junction of certain disease-related chromosomal translocations, which result in the expression of chimeric proteins that may promote tumor growth. Alternative splicing results in multiple transcript variants. |
Applications: |
ELISA, IHC |
Name of antibody: |
LPP |
Immunogen: |
Synthetic peptide of human LPP |
Full name: |
LIM domain containing preferred translocation partner in lipoma |
SwissProt: |
Q93052 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human brain and Human liver cancer |
IHC Recommend dilution: |
25-100 |