反应种属: Human Mouse
技术规格
Background:
There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain.
Applications:
WB
Name of antibody:
LIMK2(Ab-283)
Immunogen:
Synthesized non-phosphopeptide derived from human LIMK2 around the phosphorylation site of serine 283 (R-R-S(p)-L-R).
Full name:
LIM domain kinase 2
Synonyms:
0
SwissProt:
P53671
WB Predicted band size:
72 kDa
WB Positive control:
NIH/3T3 cells treated with PMA (125ng/ml, 30mins) lysate
WB Recommended dilution:
500-3000