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  • GM2A抗原(重组蛋白)

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    • 品牌 : 通蔚生物
    • 目录号 : TW11238
    • 应用 : 仅供科研使用
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中文名称:GM2A 抗原(重组蛋白)

英文名称:GM2A Antigen (Recombinant Protein)

别      名:GM2 ganglioside activator; SAP-3; GM2-AP

相关类别:抗原

储      存:冷冻(-20℃)

概述

Fusion protein corresponding to a region derived from 34-193 amino acids of human GM2A


技术规格

Full name:

GM2 ganglioside activator

Synonyms:

SAP-3; GM2-AP

Swissprot:

P17900

Gene Accession:

BC009273

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.