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021-54845833/15800441009
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Background: |
This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
LATS2 |
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Immunogen: |
Synthetic peptide of human LATS2 |
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Full name: |
large tumor suppressor kinase 2 |
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Synonyms： |
KPM |
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SwissProt: |
Q9NRM7 |
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ELISA Recommended dilution: |
1000-2000 |
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IHC positive control: |
Human thyroid cancer and Human liver cancer |
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IHC Recommend dilution: |
25-100 |
