Fusion protein corresponding to a region derived from 728-927 amino acids of human GBA2 |
技术规格
Full name: |
glucosylceramidase beta 2 |
Synonyms: |
AD035; SPG46; NLGase |
Swissprot: |
Q9HCG7 |
Gene Accession: |
BC011363 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a microsomal beta-glucosidase that catalyzes the hydrolysis of bile acid 3-O-glucosides as endogenous compounds. Studies to determine subcellular localization of this protein in the liver indicated that the enzyme was mainly enriched in the microsomal fraction where it appeared to be confined to the endoplasmic reticulum. This putative transmembrane protein is thought to play a role in carbohydrate transport and metabolism. |