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中文名称：兔抗AADAC多克隆抗体
英文名称： Anti-AADAC rabbit polyclonal antibody
别 名： DAC; CES5A1
抗 原： AADAC
储 存： 冷冻（-20℃）
宿 主： Rabbit
相关类别： 一抗
反应种属： Human
标 记 物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
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Background: |
Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens. Arylacetamide deacetylation is an important enzyme activity in the metabolic activation of arylamine substrates to ultimate carcinogens. Displays major serine hydrolase activity in liver microsomes. Hydrolyzes also flutamide, which is an antiandrogen drug used for the treatment of prostate cancer that occasionally causes severe hepatotoxicity. Displays cellular triglyceride lipase activity in liver. Increases intracellular fatty acids derived from hydrolysis of newly formed triglyceride stores. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
AADAC |
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Immunogen: |
Fusion protein of human AADAC |
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Full name: |
Arylacetamide deacetylase |
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Synonyms： |
DAC; CES5A1 |
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SwissProt: |
P22760 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human colon cancer and Human liver cancer |
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IHC Recommend dilution: |
25-100 |
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WB Predicted band size: |
46 kDa |
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WB Positive control: |
Human fetal liver and liver cancer tissue |
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WB Recommended dilution: |
500-2000 |
