兔抗KIT(Phospho-Tyr703) 多克隆抗体

Background:

This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:

WB

Name of antibody:

KIT(Phospho-Tyr703)

Immunogen:

Peptide sequence around phosphorylation site of Tyrosine 703 (A-L-Y(p)-K-N) derived from Human KIT.

Full name:

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

Synonyms：

PBT; SCFR; C-Kit; CD117

SwissProt:

P10721

WB Predicted band size:

110 kDa

WB Positive control:

HepG2 cells lysates treated with EGF

WB Recommended dilution:

500-1000