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Synthetic peptide corresponding to a region derived from 420-434 amino acids of human enolase 2 (gamma, neuronal) |
技术规格
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Full name |
Enolase 2 (gamma, neuronal) |
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Synonyms |
NSE |
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Swissprot |
P09104 |
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Gene Accession |
NP_001966 |
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Background |
This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates. Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival. |
