兔抗ACVR1C多克隆抗体

Background:

ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).

Applications:

ELISA, IHC

Name of antibody:

ACVR1C

Immunogen:

Fusion protein of human ACVR1C

Full name:

activin A receptor, type IC

Synonyms：

ALK7; ACVRLK7

SwissProt:

Q8NER5

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

15-50