Background: |
RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. May play a role as a negative regulator of cell growth. Inhibits cell proliferation. Involved in splice site selection of vascular endothelial growth factor. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. Involved in post-transcriptional regulation of HIV-1 gene expression. Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro. |
Applications: |
ELISA, IHC |
Name of antibody: |
KHDRBS3 |
Immunogen: |
Full length fusion protein |
Full name: |
KH domain containing, RNA binding, signal transduction associated 3 |
Synonyms: |
Etle; SALP; SLM2; SLM-2; TSTAR; T-STAR; etoile |
SwissProt: |
O75525 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human brain and Human esophagus cancer |
IHC Recommend dilution: |
20-100 |