Background: |
Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions |
Applications: |
WB |
Name of antibody: |
KDR (phospho-Tyr1059) |
Immunogen: |
Synthetic peptide of human KDR (phospho-Tyr1059) |
Full name: |
kinase insert domain receptor (a type III receptor tyrosine kinase) (phospho-Tyr1059) |
Synonyms: |
FLK1; CD309; VEGFR; KDR; VEGFR2 |
SwissProt: |
P35968 |
WB Predicted band size: |
152 kDa |
WB Positive control: |
HT29 cells treated with SCF-1 |
WB Recommended dilution: |
500-1000 |