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Fusion protein corresponding to a region derived from 386-578 amino acids of human EDEM2 |
技术规格
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Full name: |
ER degradation enhancing alpha-mannosidase like protein 2 |
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Synonyms: |
C20orf31; C20orf49; bA4204.1 |
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Swissprot: |
Q9BV94 |
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Gene Accession: |
BC001371 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins (Mast et al., 2005 [PubMed 15537790]). |
