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Fusion protein corresponding to a region derived from 147-350 amino acids of human DKK3 |
技术规格
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Full name: |
dickkopf WNT signaling pathway inhibitor 3 |
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Synonyms: |
RIG; REIC |
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Swissprot: |
Q9UBP4 |
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Gene Accession: |
BC007660 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. |
