兔抗KCNIP3多克隆抗体

Background:

This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described.

Applications:

ELISA, IHC

Name of antibody:

KCNIP3

Immunogen:

Fusion protein of human KCNIP3

Full name:

potassium voltage-gated channel interacting protein 3

Synonyms:

CSEN; DREAM; KCHIP3

SwissProt:

Q9Y2W7

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human brain

IHC Recommend dilution:

50-100