Background: |
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Applications: |
ELISA, IHC |
Name of antibody: |
KARS1 |
Immunogen: |
Fusion protein of human KARS1 |
Full name: |
lysyl-tRNA synthetase 1 |
Synonyms: |
KRS; KARS; KARS2; CMTRIB; DFNB89 |
SwissProt: |
Q15046 |
IHC positive control: |
Human brain and Human ovarian cancer |
IHC Recommend dilution: |
50-200 |