Background: |
The protein encoded by Gab1 is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene. |
Applications: |
WB, IF |
Name of antibody: |
GAB1 (Phospho-Tyr627) |
Immunogen: |
Synthetic peptide of human GAB1 (Phospho-Tyr627) |
Full name: |
Growth factor receptor bound protein 2-associated binding protein 1 (Phospho-Tyr627) |
SwissProt: |
Q13480 |
WB Predicted band size: |
77 kDa |
WB Positive control: |
293 cells treated with EGF |
WB Recommended dilution: |
500-1000 |
IF Positive control: |
Hela cells |
IF Recommended dilution |
100-200 |