兔抗ABI3BP多克隆抗体

Background:

A target of NESH-SH3/Abi3bp (TARSH) was originally identified as an SH3 domain-binding molecule of the NESH-SH3/Abi3 protein that is involved in Rac-dependent actin polymerization. In recent studies, TARSH gene expression was dramatically induced in mouse embryonic fibroblasts (MEFs) replicative senescence and suppressed in human lung carcinoma specimens and thyroid carcinomas. However, the molecular mechanism underlying the regulation of TARSH in tumorigenesis remains unclear.

Applications:

ELISA, IHC

Name of antibody:

ABI3BP

Immunogen:

Fusion protein of human ABI3BP

Full name:

ABI family, member 3 (NESH) binding protein

Synonyms：

TARSH; NESHBP

SwissProt:

Q7Z7G0

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human prostate cancer and human liver cancer

IHC Recommend dilution:

50-200